Mycotoxins-Myco-Binder®
Mycotoxins are secondary metabolites produced by different range of fungi that grow on raw material such as soybeans, corn, cereals and other crops. Aspergillus flavus and A. parasiticus moulds, in tropical and sub-tropical regions produce Aflatoxin affecting animal feed and human food products. In animal nutrition the economic impacts of fungal and mycotoxin contamination increases every year. Selected materials need to be treated, depending on the nature and concentration, against a wide variety of Aflatoxin, T-2, Zearalenone, Ochratoxin, and Deoxynivalenol.
Poultry vaccine response is known to be abnormal when mycotoxins are in the feed. Aflatoxin suppressed acquired immunity when pigs were challenged with an Erysipelas inoculation (Cysewski 1978). Non vaccinated pigs developed more immunity to Erysipelas than those vaccinated and fed with Aflatoxin. Cysewski stated that Aflatoxin completely off-set the benefit of vaccination. Low level Aflatoxin increased the incidence of disease of pigs challenged by swine dysentery (Joens 1981). The increased disease occurred sooner, lasted longer and caused significantly increased mortality. When fish spawn, the immune systems become suppressed by sex hormones (Wang 1995). Zearalenone, an estrogenic feed mycotoxin could intensify the hormonal effects to suppress immune function. Following the infection of shrimp with White Spot Baculovirus, haemocyte composition, especially granular cells that directly relate to phagocytosis, are dramatically decreased when mycotoxins are present (Kim 1999) |